Fig. 1

Effects of moxibustion on colon tumorigenesis in CAC mice. A schematic protocol for the experiments: AOM (10 mg/kg) via intraperitoneal injection combined with 3 cycles of DSS-free drinking water was used to establish the CAC mouse model, and the mice were subsequently subjected to moxibustion or 5-c-8HQ interventions. B Schematic diagram of the moxibustion operation. C Macroscopic observation of the colons of the mice in each group; the formation of colonic tumors is indicated by white arrows. D-H Comparison of colon length, tumor number, tumor load, maximum tumor diameter and mean tumor diameter. I HE staining of the colons of the mice in each group (scale bars, 200 μm). n = 6, compared with the NC group, ^***P<0.001; compared with the CAC group, ^#P<0.05