Fig. 4

Effects of moxibustion on lipid metabolism in CAC tumors. A 3D-PCA diagram. B Heatmap of lipid metabolism in the three groups. C Volcano plot of differential lipids between the WT-NC group and the WT-CAC group. The red dots represent lipids upregulated in the WT-CAC compared with the WT-NC, and the blue dots represent lipids downregulated in the WT-CAC compared with the WT-NC. D Volcano plot of differential lipids between the WT-CAC group and the WT-MOX group. The red dots represent lipids upregulated in WT-MOX compared with WT-CAC, and the blue dots represent lipids downregulated in WT-MOX compared with WT-CAC. E KEGG enrichment pathway analysis of differential lipids between the WT-NC group and the WT-CAC group. F KEGG enrichment pathway analysis of differential lipids between the WT-CAC group and the WT-MOX group. G Venn diagram of lipids significantly downregulated in the WT-CAC group compared with the WT-NC group and significantly upregulated in the WT-MOX group compared with the WT-CAC group. H Venn diagram of lipids significantly upregulated in the WT-CAC group compared with the WT-NC group and significantly downregulated in the WT-MOX group compared with the WT-CAC group. I Box plot of differential lipids in the three groups of mice. n = 6, ^*P<0.05, ^**P<0.01, ^***P<0.001