Fig. 3

NMF clustering of ccRCC patients. A Consensus matrix generated from NMF clustering with k = 2. B The UMAP plot demonstrating a difference in gene expression between the two clusters in the entire genome. C Differential expression of 12 pFRGs between the two clusters. D Immune infiltration patterns of two clusters. E Overall survival differences between the two clusters. F Stacked bar graph displaying differences of clinicopathological characteristics between two ccRCC clusters. BCR B-cell receptor, HR hazards ratio, MDSC myeloid-derived suppressor cell, TCR T-cell receptor, TPM transcripts per million