Fig. 4
From: SP1 promotes triple-negative breast cancer progression by targeting USP5
SP1 promotes TNBC progression by regulating USP5 expression. (A) The protein expression of SP1 and USP5 in shCtrl/231 and shSP1/231 cells in the presence or absence of overexpressed USP5. (B-F) MDA-MB-231 cell proliferation following SP1 knockdown in the presence or absence of overexpressed USP5 was evaluated using CCK8 assay (B), clonogenic assay (C, D), and EDU incorporation assay (E, F). ***P < 0.001, **P < 0.01. (G) Images of nude mice with xenograft tumors in each group. (H) Tumor growth curve of nude mice in each group. ***P < 0.001, **P < 0.01. (I) Tumor weight of nude mice in each group. ***P < 0.001