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Table 1 Logistic analysis of the correlation between OTUD3 mRNA expression and clinical characteristics in breast cancer

From: OTUD3 inhibits breast cancer cell metastasis by regulating TGF-β pathway through deubiquitinating SMAD7

Characteristics

Total (n)

OR (95% CI)

p value

Age (> 60 vs. <= 60)

1087

0.967 (0.762–1.229)

0.786

Race (Black or African American&White vs. Asian)

997

1.558 (0.912–2.663)

0.105

Menopause status (Pre&Peri vs. Post)

976

0.944 (0.713–1.250)

0.690

Pathologic T stage (T2&T3&T4 vs. T1)

1084

0.762 (0.580–1.002)

0.052

Pathologic N stage (N1&N2&N3 vs. N0)

1068

0.848 (0.667–1.078)

0.178

Pathologic M stage (M1 vs. M0)

925

0.802 (0.329–1.954)

0.627

Pathologic stage (Stage III&Stage IV vs. Stage I&Stage II)

1063

0.857 (0.648–1.133)

0.278

Histological type (Infiltrating Ductal Carcinoma vs. Infiltrating Lobular Carcinoma&Infiltrating Carcinoma NOS&Medullary Carcinoma&Mixed Histology &Mucinous Carcinoma)

1034

0.733 (0.552–0.973)

0.031*

ER status (Positive vs. Negative&Indeterminate)

1039

1.494 (1.117–1.998)

0.007*

PR status (Positive vs. Negative&Indeterminate)

1038

1.360 (1.049–1.763)

0.020*

HER2 status (Positive vs. Negative&Indeterminate)

729

0.549 (0.383–0.788)

0.001*

PAM50 (Normal&LumA&LumB&Her2 vs. Basal)

1087

1.272 (0.932–1.736)

0.130

Anatomic neoplasm subdivisions (Left vs. Right)

1087

1.105 (0.871–1.401)

0.413

  1. *p < 0.05 was considered significant