Fig. 7
From: Brachyury promotes proliferation and migration of colorectal cancer cells by targeting MMP14
MMP14 overexpression promoted CRC cell proliferation and migration. (A) Western blot analysis of MMP14 expression in HCT116 and SW480 cells transfected with EV and OE-MMP14 plasmids. Similar results were observed from three independent experiments. (B–C) CCK-8 analysis of cells transfected with EV and OE-MMP14 plasmids (n = 6). (D) Colony formation analysis of cells transfected with EV and OE-MMP14 plasmids (n = 3). (E) Quantitative analysis of (D). (F) Transwell analysis of cells transfected with OE-MMP14 plasmids (scale bar: 100 μm, n = 3). (G) Quantitative analysis of (F). Data are shown as means ± SD; *p < 0.05, ***p < 0.001; Student’s t-test